Marvel's Spider-Man 3 will feature Peter Parker in a significant role, despite the cliffhanger ending of Spider-Man 2, according to Yuri Lowenthal, the voice actor for the character.
In an interview with The Direct, Lowenthal confirmed Parker's continued presence in the anticipated, though yet unannounced, Marvel's Spider-Man 3. He stated, "While I can't reveal much about the game, I can confirm that Peter isn't gone. He'll be actively involved in the next game; he won't be sidelined, I assure you."
Spoilers for Marvel’s Spider-Man 2 follow.